Publications of the Consortium linked to their respective Work Package

WP1: Project Management

WP2:Collection bank & harmonization

WP3: Genotyping & serotyping

68) Martín-Valls GE, Kvisgaard LK, Tello M, Darwich L, Cortey M, Burgara-Estrella AJ, Hernández J, Larsen LE, Mateu E., 2014, Analysis of ORF5 and full-length genome sequences of porcine reproductive and respiratory syndrome virus isolates of genotypes 1 and 2 retrieved worldwide provides evidences supporting that recombination is a common phenomenon and may produce mosaic isolates. J Virol. Dec 26. Mar;88(6):3170-81.

67) Lu ZH, Brown A, Wilson AD, Calvert JG, Balasch M, Fuentes-Utrilla P, Loecherbach J, Turner F, Talbot R, Archibald AL, Ait-Ali T., 2014, Genomic variation in macrophage-cultured European porcine reproductive and respiratory syndrome virus Olot/91 revealed using ultra-deep next generation sequencing. Virol J. Mar 4;11(1):42.

65)
Kvisgaard LK, Hjulsager CK, Brar MS, Leung FC, Larsen LE., 2013, Genetic dissection of complete genomes of Type 2 PRRS viruses isolated in Denmark over a period of 15 years. Vet Microbiol. Dec 27;167(3-4):334-44.

62)
Kvisgaard LK, Hjulsager CK, Kristensen CS, Lauritsen KT, Larsen LE., 2013, Genetic and antigenic characterization of complete genomes of Type 1 Porcine Reproductive and Respiratory Syndrome viruses (PRRSV) isolated in Denmark over a period of 10 years. Virus Res. Dec 26;178(2):197-205.

55) Kvisgaard LK, Hjulsager CK, Fahnøe U, Breum SO, Ait-Ali T, Larsen LE, 2013, A fast and robust method for full genome sequencing of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Type 1 and Type 2. J. Virol. Methods Jul 24;193(2):697-705.

54) Fabisiak M, Podgórska K, Skrzypiec E, Szczotka A, Stadejek T., 2013, Detection of porcine circovirus type 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) antibodies in meat juice samples from Polish wild boar (Sus scrofa L.). Acta Vet Hung. Jul 16:1-8.

53)
Stadejek T, Stankevicius A, Murtaugh MP, Oleksiewicz MB., 2013, Molecular evolution of PRRSV in Europe: Current state of play. Vet Microbiol. Jul 26;165(1-2):21-8.

45) Badaoui B, Grande R, Calza S, Cecere M, Luini M, Stella A, Botti S., 2013, Impact of genetic variation and geographic distribution of porcine reproductive and respiratory syndrome virus on infectivity and pig growth. BMC Vet Res. 2013 Mar 27;9:58.

29)
Díaz I Venteo A, Rebollo B, Martín-Valls GE, Simon-Grifé M, Sanz A, Mateu E., 2012, Comparison of two commercial enzyme-linked immunosorbent assays for the diagnosis of Porcine reproductive and respiratory syndrome virus infection. J Vet Diagn Invest. 24(2):344-8.

25)
Stadejek T, Podgorska K, Porowski M, Jabłoński A, Pejsak Z., 2011, Linked outbreaks and control of porcine reproductive and respiratory syndrome and postweaning multisystemic wasting syndrome in a pig farm in Poland. Vet Rec. Oct 22;169(17):441.

15) Van Breedam W, Costers S, Vanhee M, Gagnon CA, Rodríguez-Gómez IM, Geldhof M, Verbeeck M, Van Doorsselaere J, Karniychuk U, Nauwynck HJ., 2011, Porcine reproductive and respiratory syndrome virus (PRRSV)-specific mAbs: supporting diagnostics and providing new insights into the antigenic properties of the virus. Vet Immunol Immunopathol. 141(3-4): 246-257

10) Darwich L, Gimeno M, Sibila M, Diaz I, de la Torre E, Dotti S, Kuzemtseva L, Martin M, Pujols J, Mateu E., 2011, Genetic and immunobiological diversities of porcine reproductive and respiratory syndrome genotype I strains. Vet. Microb. 150(1-2):49-62.

7)
Murtaugh MP, Stadejek T, Abrahante JE, Lam TT, Leung FC., 2010, The ever-expanding diversity of porcine reproductive and respiratory syndrome virus. Virus Research 154(1-2): 18-30.

WP4: Pathogenesis & virulence


74) Li Y, Zhou L, Zhang J, Ge X, Zhou R, Zheng H, Geng G, Guo X, Yang H, 2014, Nsp9 and Nsp10 Contribute to the Fatal Virulence of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Emerging in China. PLOS Pathog. 10(7): e 1004216.

71)
Badaoui B, Rutigliano T, Anselmo A, Vanhee M, Nauwynck H, Giuffra E, Botti S., 2014, RNA-Sequence Analysis of Primary Alveolar Macrophages after In Vitro Infection with Porcine Reproductive and Respiratory Syndrome Virus Strains of Differing Virulence. PLoS One Mar 18;9(3):e91918.

70) Zheng H, Zhang K, Zhu XQ, Liu C, Lu J, Gao F, Zhou Y, Zheng H, Lin T, Li L, Tong G, Wei Z, Yuan S., 2014, Genetic manipulation of a transcription-regulating sequence of porcine reproductive and respiratory syndrome virus reveals key nucleotides determining its activity. Arch Virol 159:1927–1940.

66) García-Nicolás O, Baumann A, Vielle NJ, Gómez-Laguna J, Quereda JJ, Pallarés FJ, Ramis G, Carrasco L, Summerfield A., 2013, Virulence and genotype-associated infectivity of interferon-treated macrophages by porcine reproductive and respiratory syndrome viruses. Virus Res. Nov 9. pii: S0168-1702(13)00288-8. doi: 10.1016/j.virusres.2013.08.009.

64)
Weesendorp E, Stockhofe-Zurwieden N, Popma-De Graaf DJ, Fijten H, Rebel JM, 2013, Phenotypic modulation and cytokine profiles of antigen presenting cells by European subtype 1 and 3 porcine reproductive and respiratory syndrome virus strains in vitro and in vivo. Vet Microbiol. Dec 27;167(3-4):638-50.

59)
Karniychuk UU, Nauwynck HJ., 2013, Pathogenesis and prevention of placental and transplacental porcine reproductive and respiratory syndrome virus infection. Vet Res. Oct 7;44(1):95.

58)
Frydas IS, Verbeeck M, Cao J, Nauwynck HJ., 2013, Replication characteristics of porcine reproductive and respiratory syndrome virus (PRRSV) European subtype 1 (Lelystad) and subtype 3 (Lena) strains in nasal mucosa and cells of the monocytic lineage: indications for the use of new receptors of PRRSV (Lena). Vet Res. Sep 4;44(1):73.

52)
Van Breedam W, Verbeeck M, Christiaens I, Van Gorp H, Nauwynck HJ., 2013, Porcine, murine and human sialoadhesin (Sn / Siglec-1 / CD169): portals for porcine reproductive and respiratory syndrome virus (PRRSV) entry into target cells. J Gen Virol. Jun 5

51) Karniychuk UU, De Spiegelaere W, Nauwynck HJ., 2013, Porcine reproductive and respiratory syndrome virus infection is associated with an increased number of Sn-positive and CD8-positive cells in the maternal-fetal interface. Virus Res. May 23

48) Yin Y, Liu C, Liu P, Yao H, Wei Z, Lu J, Tong G, Gao F, Yuan S., 2013, Conserved nucleotides in the terminus of the 3' UTR region are important for the replication and infectivity of porcine reproductive and respiratory syndrome virus.
Arch Virol. Mar 13.

47) Gao F, Yao H, Lu J, Wei Z, Zheng H, Zhuang J, Tong G, Yuan S., 2013, Replacement of the heterologous 5' untranslated region allows preservation of the fully functional activities of type 2 porcine reproductive and respiratory syndrome virus. Virology. Apr 25;439(1):1-12.

43) Sun L, Li Y, Liu R, Wang X, Gao F, Lin T, Huang T, Yao H, Tong G, Fan H, Wei Z, Yuan S., 2013, Porcine reproductive and respiratory syndrome virus ORF5a protein is essential for virus viability. Virus Res. Jan;171(1):178-85.

40)
Morgan SB, Graham SP, Salguero FJ, Sánchez Cordón PJ, Mokhtar H, Rebel JM, Weesendorp E, Bodman-Smith KB, Steinbach F, Frossard JP., 2012, Increased pathogenicity of European porcine reproductive and respiratory syndrome virus is associated with enhanced adaptive responses and viral clearance. Vet Microbiol. Nov. 29.

39)
Weesendorp E, Morgan S, Stockhofe-Zurwieden N, Graaf DJ, Graham SP, Rebel JM., 2012, Comparative analysis of immune responses following experimental infection of pigs with European porcine reproductive and respiratory syndrome virus strains of differing virulence. Vet Microbiol. Sep 19.

35)
Wei Z, Lin T, Sun L, Li Y, Wang X, Gao F, Liu R, Chen C, Tong G, Yuan S., 2012, N-Linked Glycosylation of GP5 of Porcine Reproductive and Respiratory Syndrome Virus Is Critically Important for Virus Replication In Vivo. J Virol. 86(18):9941-51

33)
Wei Z, Tian D, Sun L, Lin T, Gao F, Liu R, Tong G, Yuan S., 2012, Influence of N-linked glycosylation of minor proteins of porcine reproductive and respiratory syndrome virus on infectious virus recovery and receptor interaction. Virology Jul 20;429(1):1-11.

31)
Karniychuk UU, Breedam WV, Roy NV, Rogel-Gaillard C, Nauwynck HJ., 2012, Demonstration of microchimerism in pregnant sows and effects of congenital PRRSV infection. Vet Res. 2012 Mar 16;43(1):19.

30)
Zhang R, Chen C, Sun Z, Tan F, Zhuang J, Tian D, Tong G, Yuan S., 2012, Disulfide linkages mediating nucleocapsid protein dimerization are not required for porcine arterivirus infectivity. J Virol. 86(8):4670-81.

28)
Tian D, Wei Z, Zevenhoven-Dobbe JC, Liu R, Tong G, Snijder EJ, Yuan S., 2012, Arterivirus minor envelope proteins are a major determinant of viral tropism in cell culture. J Virol. 86:3701-12.

27) Nauwynck, H.J., Van Gorp, H., Vanhee, M., Karniychuk, U., Geldhof, M., Cao, A., Verbeeck, M., Van Breedam, W., 2012, Micro-dissecting the pathogenesis and immune response of PRRSV infection paves the way for more efficient PRRSV vaccines. Transboundary and Emerging Diseases 59 (Suppl. 1): 1-5.

23)
Gao F, Lu J, Yao H, Wei Z, Yang Q, Yuan S., 2012, Cis-acting structural element in 5' UTR is essential for infectivity of porcine reproductive and respiratory syndrome virus. Virus Res. 163(1):108-19.

22) Karniychuk UU, Saha D, Geldhof M, Vanhee M, Cornillie P, Van den Broeck W, Nauwynck HJ., 2011, Porcine reproductive and respiratory syndrome virus (PRRSV) causes apoptosis during its replication in fetal implantation sites. Microb Pathog. 51(3):194-202

18
) Lu J., Gao F., Wei Z., Liu P., Liu C., Zheng H., Li Y., Lin T., Yuan S., 2011, A 5’-Proximal Stem-loop Structure of 5’ Untranslated Region of Porcine Reproductive and Respiratory Syndrome Virus Genome Is Key for Virus Replication. Virology Journal 8: 172

17)
Tan F., Wei Z., Li Y., Zhang R., Zhuang J., Sun Z., Yuan S., 2011, Identification of non-essential regions in nucleocapsid protein of Porcine and Respiratory Syndrome Virus for replication in cell culture. Virus Research 158 (1-2):62-71

12)
Tian D., Zheng H., Zhang R., Zhuang J., Yuan S., 2011. Chimeric Porcine Reproductive and Respiratory Syndrome Viruses reveal full function of genotype 1 envelope proteins in the backbone of genotype 2. Virology 412: 1-8

3) Karniychuk UU, Geldhof M, Vanhee M, Van Doorsselaere J, Saveleva TA, Nauwynck HJ, 2010, Pathogenesis and antigenic characterization of a new East European subtype 3 porcine reproductive and respiratory syndrome virus isolate. BMC Veterinary Research 6:30

2) Van Breedam W, Delputte PL, Van Gorp H, Misinzo G, Vanderheijden N, Duan X, Nauwynck HJ, 2010, Porcine reproductive and respiratory syndrome virus entry into the porcine macrophage. J. Gen. Virol. 91:1659-67. Review

WP5: Immunobiology of PRRS

73) Mokhtar H, Eck M, Morgan SB, Essler SE, Frossard JP, Ruggli N, Graham SP., 2014, Proteome-wide screening of the European porcine reproductive and respiratory syndrome virus reveals a broad range of T cell antigen reactivity. Vaccine. 2014 May 17. pii: S0264-410X(14)00592-1. doi: 10.1016/j.vaccine.2014.04.054.

69)
Liudmila Kuzemtsevaa, Eugenia de la Torre, Gerard Martína, Ferran Soldevila, Tahar Ait-Ali, Enric Mateu, Laila Darwich, 2014, Regulation of toll-like receptors 3, 7 and 9 in porcine alveolar macrophages by different genotype 1 strains of porcine reproductive and respiratory syndrome virus. Vet Immunol Immunopathol. Apr 15;158(3-4):189-98.

66)
García-Nicolás O, Baumann A, Vielle NJ, Gómez-Laguna J, Quereda JJ, Pallarés FJ, Ramis G, Carrasco L, Summerfield A., 2013, Virulence and genotype-associated infectivity of interferon-treated macrophages by porcine reproductive and respiratory syndrome viruses. Virus Res. Nov 9. pii: S0168-1702(13)00288-8. doi: 10.1016/j.virusres.2013.08.009.

64) Weesendorp E, Stockhofe-Zurwieden N, Popma-De Graaf DJ, Fijten H, Rebel JM, 2013, Phenotypic modulation and cytokine profiles of antigen presenting cells by European subtype 1 and 3 porcine reproductive and respiratory syndrome virus strains in vitro and in vivo. Vet Microbiol. Dec 27;167(3-4):638-50.


50)
Dawson HD, Loveland JE, Pascal G, Gilbert JG, Uenishi H, Mann KM, Sang Y, Zhang J, Carvalho-Silva D, Hunt T, Hardy M, Hu Z, Zhao SH, Anselmo A, Shinkai H, Chen C, Badaoui B, Berman D, Amid C, Kay M, Lloyd D, Snow C, Morozumi T, Cheng RP, Bystrom M, Kapetanovic R, Schwartz JC, Kataria R, Astley M, Fritz E, Steward C, Thomas M, Wilming L, Toki D, Archibald AL, Bed'hom B, Beraldi D, Huang TH, Ait-Ali T, Blecha F, Botti S, Freeman TC, Giuffra E, Hume DA, Lunney JK, Murtaugh MP, Reecy JM, Harrow JL, Rogel-Gaillard C, Tuggle CK., 2013, Structural and functional annotation of the porcine immunome. BMC Genomics. 2013 May 15;14:332.

49) Baumann A, Mateu E, Murtaugh MP, Summerfield A., 2013, Impact of genotype 1 and 2 of porcine reproductive and respiratory syndrome viruses on interferon-α responses by plasmacytoid dendritic cells. Vet Res. May 15;44(1):33.

46) Badaoui B, Tuggle CK, Hu Z, Reecy JM, Ait-Ali T, Anselmo A, Botti S., 2013, Pig immune response to general stimulus and to porcine reproductive and respiratory syndrome virus infection: a meta-analysis approach. BMC Genomics. Apr 3;14:220.
44)
Burgara-Estrella A, Díaz I, Rodríguez-Gómez IM, Essler SE, Hernández J, Mateu E., 2013, Predicted peptides from non-structural proteins of porcine reproductive and respiratory syndrome virus are able to induce IFN-γ and IL-10. Viruses. Feb 11;5(2):663-77.

32) Diaz I, Gimeno M, Darwich L, Navarro N, Kuzemtseva L, Lopez S, Galindo I, Segales J, Martin M, Pujols J, Mateu E., 2012, Characterization of homologous and heterologous adaptive immune responses in porcine reproductive and respiratory syndrome virus infection. Vet Res. Apr 19;43(1):30.

19) Vanhee M, Van Breedam W, Costers S, Geldhof M, Noppe Y, Nauwynck H., 2011, Characterization of antigenic regions in the porcine reproductive and respiratory syndrome virus by the use of peptide-specific serum antibodies. Vaccine 29(29-30):4794-4804

8)
Costers S, Vanhee M, Van Breedam W, Van Doorsselaere J, Geldhof M, Nauwynck HJ., 2010, GP4-specific neutralizing antibodies might be a driving force in PRRSV evolution. Virus Research 154(1-2):104-113. Review

6)
Vanhee M, Costers S, Van Breedam W, Geldhof MF, Van Doorsselaere J, Nauwynck HJ., 2010, A variable region in GP4 of European-type porcine reproductive and respiratory syndrome virus induces neutralizing antibodies against homologous but not heterologous virus strains. Viral Immunology 23(4):403-413

WP6: Inactivated marker vaccines

63) Geldhof MF, Van Breedam W, De Jong E, Lopez Rodriguez A, Karniychuk UU, Vanhee M., Van Doorsselaere J, Maes D, Nauwynck HJ, 2013, Antibody response and maternal immunity upon boosting PRRSV-immune sows with experimental farm-specific and commercial PRRSV vaccines. Vet Microbiol. Dec 27;167(3-4):260-71.


38)
Geldhof MF, Vanhee M, Van Breedam W, Van Doorsselaere J, Karniychuk UU, Nauwynck HJ., 2012, Comparison of the efficacy of autogenous inactivated Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) vaccines with that of commercial vaccines against homologous and heterologous challenges. BMC Vet Res. Oct 3;8(1):182.

37)
Karniychuk UU, Saha D, Vanhee M, Geldhof M, Cornillie P, Caij AB, De Regge N, Nauwynck HJ., 2012, Impact of a novel inactivated PRRS virus vaccine on virus replication and virus-induced pathology in fetal implantation sites and fetuses upon challenge. Theriogenology. 78(7):1527-37.

34) Delrue I, Verzele D, Madder A, Nauwynck HJ., 2012, Inactivated virus vaccines from chemistry to prophylaxis: merits, risks and challenges. Expert Rev Vaccines 11(6):695-719.

WP7:Recombinant live marker vaccines

75) Becares M, Sanchez CM, Sola I, Enjuanes L, Zuñiga S, 2014, Antigenic structures stably expressed by recombinant TGEV-derived vectors. Virology. Aug 6;464-465C:274-286.


4)
Cruz J.L., Zuñiga S., Becares M., Sola I., Ceriani J.E., Juanola S., Plana J. and Enjuanes L., 2010, Vectored vaccines to protect against PRRSV. Virus Res. 154:150-60

WP8: Attenuated marker vaccines

41) Wang X, Sun L, Li Y, Lin T, Gao F, Yao H, He K, Tong G, Wei Z, Yuan S., 2013, Development of a differentiable virus via a spontaneous deletion in the nsp2 region associated with cell adaptation of porcine reproductive and respiratory syndrome virus. Virus Res, Jan;171(1):150-160.

36)
Lin T, Li X, Yao H, Wei Z, Tan F, Liu R, Sun L, Zhang R, Li W, Lu J, Tong G, Yuan S., 2012, Use of reverse genetics to develop a novel marker porcine reproductive and respiratory syndrome virus. Virus Genes. Dec;45(3):548-55.

WP9: In vitro and in vivo testing of candidate vaccines

75) Becares M, Sanchez CM, Sola I, Enjuanes L, Zuñiga S, 2014, Antigenic structures stably expressed by recombinant TGEV-derived vectors. Virology. Aug 6;464-465C:274-286.

72) Trus I, Bonckaert C, van der Meulen K, Nauwynck HJ., 2014, Efficacy of an attenuated European subtype 1 porcine reproductive and respiratory syndrome virus (PRRSV) vaccine in pigs upon challenge with the East European subtype 3 PRRSV strain Lena. Vaccine. Apr 4. pii: S0264-410X(14)00458-7. doi: 10.1016/j.vaccine.2014.03.077.

63)
Geldhof MF, Van Breedam W, De Jong E, Lopez Rodriguez A, Karniychuk UU, Vanhee M., Van Doorsselaere J, Maes D, Nauwynck HJ, 2013, Antibody response and maternal immunity upon boosting PRRSV-immune sows with experimental farm-specific and commercial PRRSV vaccines. Vet Microbiol. Dec 27;167(3-4):260-71.

41) Wang X, Sun L, Li Y, Lin T, Gao F, Yao H, He K, Tong G, Wei Z, Yuan S., 2013, Development of a differentiable virus via a spontaneous deletion in the nsp2 region associated with cell adaptation of porcine reproductive and respiratory syndrome virus. Virus Res, Jan;171(1):150-160.


38) Geldhof MF, Vanhee M, Van Breedam W, Van Doorsselaere J, Karniychuk UU, Nauwynck HJ., 2012, Comparison of the efficacy of autogenous inactivated Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) vaccines with that of commercial vaccines against homologous and heterologous challenges. BMC Vet Res. Oct 3;8(1):182.

37) Karniychuk UU, Saha D, Vanhee M, Geldhof M, Cornillie P, Caij AB, De Regge N, Nauwynck HJ., 2012, Impact of a novel inactivated PRRS virus vaccine on virus replication and virus-induced pathology in fetal implantation sites and fetuses upon challenge. Theriogenology. 78(7):1527-37.

36) Lin T, Li X, Yao H, Wei Z, Tan F, Liu R, Sun L, Zhang R, Li W, Lu J, Tong G, Yuan S., 2012, Use of reverse genetics to develop a novel marker porcine reproductive and respiratory syndrome virus. Virus Genes. Dec;45(3):548-55.

WP10: DIVA serological assays

41) Wang X, Sun L, Li Y, Lin T, Gao F, Yao H, He K, Tong G, Wei Z, Yuan S., 2013, Development of a differentiable virus via a spontaneous deletion in the nsp2 region associated with cell adaptation of porcine reproductive and respiratory syndrome virus. Virus Res, Jan;171(1):150-160.

36)
Lin T, Li X, Yao H, Wei Z, Tan F, Liu R, Sun L, Zhang R, Li W, Lu J, Tong G, Yuan S., 2012, Use of reverse genetics to develop a novel marker porcine reproductive and respiratory syndrome virus. Virus Genes. Dec;45(3):548-55.

15) Van Breedam W, Costers S, Vanhee M, Gagnon CA, Rodríguez-Gómez IM, Geldhof M, Verbeeck M, Van Doorsselaere J, Karniychuk U, Nauwynck HJ., 2011, Porcine reproductive and respiratory syndrome virus (PRRSV)-specific mAbs: supporting diagnostics and providing new insights into the antigenic properties of the virus. Vet Immunol Immunopathol. 141(3-4): 246-257

Other publications of the Consortium linked to the project


61) Morales L., Mateos-Gomez P.A., Capiscol C., del Palacio L., Enjuanes L., and Sola I., 2013, Transmissible gastroenteritis coronavirus genome packaging signal is located at the 5’ end of the genome and promotes viral RNA incorporation into virions in a replication-independent process. J. Virol. 87:11579-90


60) Wang C., Huang B., Kong N., Li Q., Ma Y., Li Z., Gao J., Zhang C., Wang X., Liang C., Dang L., Xiao S., Mu Y., Zhao Q., Sun Y., Almazan F., Enjuanes L., and Zhou E.M., 2013, A novel porcine reproductive and respiratory syndrome virus vector system that stably expresses enhanced green fluorescent protein as a separate transcription unit. Vet Res. Oct 31; 44:104.

57)
Cruz J.L.G., Becares M., Sola I., Oliveros J.C., Enjuanes L, and Zuñiga S., 2013, Alphacoronavirus protein 7 modulates host innate immune response and is an interferon antagonist. J. Virol. 87:9754-67

56) Thuenemann E.C., Lenzi P., Love A.J., Taliansky M., Becares M., Zuñiga S., Enjuanes L., Zahmanova G.G., Minkov I.N., Matic S., Noris E., Meyers A., Hattingh A., Rybicki E.P., Kiselev O.I., Ravin N.V., Eldarov M.A., Skryabin K.G. and Lomonossoff G.P., 2013, The use of transient expression systems for the rapid production of virus-like particles in plants. Curr. Pharm. Design 19:5564-73


42)
Mateos-Gomez PA, Morales L, Zuñiga S, Enjuanes L, Sola I., 2013, Long-distance RNA-RNA interactions in the coronavirus genome form high-order structures promoting discontinuous RNA synthesis during transcription. J Virol. Jan;87(1):177-86.

26)
Nogales A, Márquez-Jurado S, Galán C, Enjuanes L, Almazán F., 2012, Transmissible gastroenteritis coronavirus RNA dependent RNA polymerase and the nonstructural proteins 2, 3 and 8 are incorporated into viral particles. J Virol. 86:1261-6.

24)
Zhou Y, Zheng H, Gao F, Tian D, Yuan S., 2011, Mutational analysis of the SDD sequence motif of a PRRSV RNA-dependent RNA polymerase. Sci China Life Sci. Sep;54(9):870-9.

21) Mateos-Gomez P.A., Zuñiga S., Palacio L., Enjuanes L. and Sola I., 2011, Gene N proximal and distal RNA motifs regulate coronavirus nucleocapsid mRNA transcription. J. Virol. 85:8968-80.

20) Cruz J.L.G., Sola I., Becares M., Alberca B., Plana J., Enjuanes L. and Zuñiga S., 2011, Coronavirus gene 7 counteracts host defenses and modulates virus virulence. Plos Pathog. 7(6):e1002090

16) Sola I., Galan C., Mateos-Gomez P.A., Palacio L., Zuñiga S., Almazan F. and Enjuanes L., 2011, The polypyrimidine tract-binding protein affects coronavirus RNA accumulation levels and relocalizes viral RNAs to novel cytoplasmic domains different from replication-transcription sites. J. Virol. 85:5136-49

14)
Dufour D., Mateos-Gomez P.A., Enjuanes L. and Sola I., 2011, Structure and functional relevance of a transcription-regulating sequence involved in coronavirus discontinuous RNA synthesis. J. Virol. 85:4963-73

13)
Sola I., Mateos-Gomez P.A., Almazan F., Zuñiga S. and Enjuanes L., 2011, RNA-RNA and RNA-protein interactions in coronavirus replication and transcription. RNA Biol. 8:237-48

11)
Ribes J.M., Ortego J., Ceriani J., Montava R., Enjuanes L. and Buesa J., 2011, Transmissible gastroenteritis virus (TGEV)-based vectors with engineered murine tropism express the rotavirus VP7 protein and immunize mice against rotavirus. Virology 410:107-18

9)
Reguera J., Ordoño D., Santiago C., Enjuanes L. and Casasnovas J.M., 2011, Antigenic modules in the N-terminal S1 region of the transmissible gastroenteritis virus spike protein. J. Gen. Virol. 92:1117-26

5)
Zheng H., Liu C., Zhuang J, and Yuan S., 2010, Baculovirus expression of clonal porcine Arterivirus generates infectious particles in both insect and mammalian cells. Journal of Biotechnology. 150 (2):251-258

1)
Zuñiga S., Cruz J.L., Sola I., Mateos-Gomez P.A., Palacio L. and Enjuanes L., 2010, Coronavirus nucleocapsid protein facilitates template switching and is required for efficient transcription. J. Virol. 84:2169-75










Other Dissemination activities linked to PoRRSCon

Lise Kirstine Kvisgaard, 2013, Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). PhD Thesis; Technical University of Denmark, Frederiksberg, Denmark. ISBN 978-87-992685-8-0

Proceedings of the 2013 International PRRS Symposium and PCVAD(PCV2)
Co-organized by Prof. Hanchun Yang, CAU, China National Conference Center Beijing, China, May 20-22, 2013

European Union, 2012, A decade of EU-funded animal health research. ISBN 978-92-79-21035-8 doi:10.2777/73975

Nauwynck, H., 2010, Going the whole hog. International Innovation Dec 2010, 24-26.





Please note the direct link to the abstract/pdf of each publication highlighted in white in the list above.